您的位置: 首页 > 农业专利 > 详情页

AGENT INDUCING IMMUNITY
专利权人:
ТОРЭЙ ИНДАСТРИЗ; ИНК. (JP)
发明人:
ОКАНО Фумиеси (JP),СИМИДЗУ Масаки (JP),САИТО Таканори (JP)
申请号:
RU2013156620/10
公开号:
RU2013156620A
申请日:
2013.12.19
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. An immunity-inducing agent containing an effective amount of at least one polypeptide having an immunity-inducing activity that induces CD8 + cytotoxic T cells capable of killing tumor cells expressing a human CAPRIN-1 polypeptide and selected from the following polypeptides (a), ( b) and (c), or an effective amount of a recombinant vector containing a polynucleotide encoding the specified polypeptide and capable of expressing the specified polypeptide in vivo: (a) an amino acid polypeptide after the sequence of SEQ ID NO: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, or 30; (b) a polypeptide that is 80% or more identical to the polypeptide ( but); and (c) a polypeptide containing the polypeptide (a) or (b). 2. An immunity inducing agent according to claim 1, wherein the polypeptide (b) is a polypeptide that is 95% or more identical to polypeptide (a). 3. The immunity inducing agent according to claim 1, wherein the polypeptide having immunity inducing activity is a polypeptide with the amino acid sequence of SEQ ID NO: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28 or 30.4. The immunity inducing agent according to any one of paragraphs. 1-3, which contains as an active ingredient one or many types of the specified polypeptide. 5. An immunity inducing agent according to claim 4, wherein said polypeptide is a means for treating an antigen-percenting cell. The immunity inducing agent according to any one of paragraphs. 1-3, which is used to treat or prevent cancer in animals. 7. The immunity inducing agent according to claim 6, wherein the cancer is breast cancer, a brain tumor, leukemia, lymphoma, lung cancer, esophageal cancer or colorectal cancer1. Индуцирующий иммунитет агент, содержащий эффективное количество по меньшей мере одного полипептида, обладающего индуцирующей иммунитет активностью, который индуцирует CD8+ цитотоксические Т-клетки, способные уничтожать опухолевые клетки, экспрессирующие полипептид CAPRIN-1 человека, и выбранного из следующих
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充