TGF-ß INHIBITORS

• 收藏
• 分享

专利权人:

RIGEL PHARMACEUTICALS, INC.;RIGEL PHARMACEUTICALS; INC.;BRISTOL-MYERS SQUIBB COMPANY

发明人:

KINSELLA, Todd,GELMAN, Marina,HONG, Hui,DARWISH, Ihab, S.,SINGH, Rajinder,YU, Jiaxin,BORZILLERI, Robert, M.,VELAPARTHI, Upender,LIU, Peiying,DARNE, Chetan,RAHAMAN, Hasibur,WARRIER, Jayakumar, Sankara

申请号：

SG11201705821X

公开号：

SG11201705821XA

申请日:

2016.02.26

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, A, Z, R1 and R′ are as described herein. In certain embodiments, a compound disclosed herein inhibits TGF-β, and can be used to treat disease by blocking TGF-β signaling.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/