The present relates to compounds of the General formula (1), their tautomeric forms, stereoisomers, pharmaceutically acceptable salts, Pharmaceutical compositions containing them, Methods for their preparation, use of these compounds in Medicine and intermediate products which are or Tilizan in its Development.This leads to compounds that can be used to treat diseases such as hyperlipidemia and also have a beneficial effect on cholesterol.Claim 1: compounds of the formula (1) characterized by its tautomeric forms, stereoisomers, pharmaceutically acceptable Salts and pharmaceutically acceptable compositions containing a group where a represents optionally substituted or FUSED elected of the simple Heterociclil or aryl groups, cicloalquil； represents the alkyl groups C1 and C2 - 6 - 6, alquenil UnitedSubstituted or unsubstituted, linear or branches, or the groups represented by M - (CH2) - U, where u represents o, S (OR) or NR4； M represents integers from 2 to 4, or represents integers from 0 to 2 and R4 represents h, alkyl or substituted C1 - 6 no linear or branched alkyl substituted C1 - 6； Z represents A single group or optionally substituted aryl groups merged.Heterociclil or cicloalquil； X represents a Union or can be selected, or s (OR) or R4 or NR4 where defined above； W represents alkyl groups C1 C2 - 6 - 6, alquenil linear or branched, substituted or unsubstituted； r1 represents Hydrogen, optionally substituted groups Alkyl cicloalquil C1 - C3 - 6, 6, alcoxialquil, hidroxialquil, aminoalquil, aryl, heterociclil, aralquil,Heterociclilalquil； R2 represents Hydrogen, alkyl or selected groups of C1 - 6, aryl, heterociclil, aralquil heterociclilalquil alkoxy, C1, C1 tioalquil hidroxialquil, - 6, - 6, amino, aminoalquil, alquilamino, each of which can be optionally replaced； R1 and R2 when s Possible ad,Together they can Form 4 to 7 Member Rings with saturated or partially saturated containing 0 - 2 additional heteroatoms selected from the group of N, o and S (OR)
