A method correcting pathological human skin conditions caused by aging provides reduction of clinical signs of skin aging and improves functional skin parameters by using the patient's autogenous fibroblasts and their further introduction to the patient, where material is sampled, and cells are grown with further isolation of the patient's fibroblast culture. Genetic research of the fibroblast culture is conducted by determining the DNA sequence and the activity of the genes selected from the group including TGFB1, TGFBR2, COL1A1, COL1A2, SOD1, SOD2, GPX1, GPX3, CLCA2. Findings are compared with normal DNA sequences and the data of the normal expression level of the respective genes. Genetic constructs are created with the cDNAs of the patient's genes the activity of which is modified, or the DNA structure of which has deviations. These genetic constructs are embedded in the patient's fibroblast culture. Then these modified autogenous fibroblasts are injected to the patient.
