Li Chen;Michael Patrick Dillon;Ronald Charles Hawley;Minmin Yang;Lichun Feng
发明人:
Li Chen,Michael Patrick Dillon,Lichun Feng,Ronald Charles Hawley,Minmin Yang
申请号：
US12843563
公开号：
US20120022067A1
申请日:
2010.07.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1 is a group of formula A or formula B,and X, R2, R3, R4, R5, R6, Ra and Rb are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the subject compounds.
