עכברים מותאמים גנטית המבטאים מוליקולות מסוג ii של mhc כימרי

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专利权人:

REGENERON PHARMACEUTICALS INC.

发明人:

申请号：

IL24356516

公开号：

IL243565A

申请日:

2016.01.11

申请国别(地区):

IL

年份:

2017

代理人:

摘要：

The invention provides genetically modified non-human animals that express a humanized MHC II protein (humanized MHC II ± and ² polypeptides), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/