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Method of Treating Cancer Using a cMET and AXL Inhibitor and an ErbB Inhibitor
专利权人:
GlaxoSmithKline
发明人:
Tona M. Gilmer,James G. Greger, JR.,Li Liu,Hong Shi
申请号:
US13753146
公开号:
US20130150363A1
申请日:
2013.01.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a method of treating cancer in a patient comprising administering to the patient therapeutically effective amounts of:a) a compound of formula A:or a pharmaceutically acceptable salt thereof, wherein R1-R4, p, and q are as defined and(b) an erbB inhibitor that inhibits erbB-1 or erbB-2 or erbB-3 receptor or a combination thereof. The method of the present invention addresses a need in the art with the discovery of a combination therapy that shows evidence of being a more effective therapy than previously disclosed therapies.
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