HETEROCYCLE COMPOUNDS AS TYRO3, AXL AND MERTK (TAM) FAMILY OF RECEPTOR TYROSINE KINASE INHIBITORS

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专利权人:

DEVELOPMENT CENTER FOR BIOTECHNOLOGY

发明人:

YEN, Shih-Chieh,LIAO, Chu-Bin,WANG, Hui-Chen,CHEN, Po-Ting,PAN, Yu-Chih,LI, Tsung-Hui,CHEN, Bo-Rong,CHIOU, Shian-Yi

申请号：

SG11202005983T

公开号：

SG11202005983TA

申请日:

2018.12.26

申请国别(地区):

SG

年份:

2020

代理人:

摘要：

Disclosed are compounds of formula (I) below and tautomers, stereoisomers, isotopologues, or pharmaceutically acceptable salts thereof: in which each of variables R1, ring A, L, W, V, and G is defined herein. Also disclosed are a method for treating disease or disorder mediated by Tyro3, Axl, and/or Mer kinase with a compound of formula (I) or a tautomer, stereoisomer, isotopologue, or salt thereof and a pharmaceutical composition containing same.

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http://www.ckcest.cn/home/