Particulate structures comprising a particulate extracellular matrix (ECM) component encased in a biornaterial composition, which, when administered to damaged cardiovascular tissue, induce modulated healing. The present invention is directed to non-antigenic, resilient, bioremodelable, biocompatible tissue prostheses that can be engineered into a variety of shapes and used to repair, augment, or replace mammalian tissues and organs. The present invention is also directed to particulate structures for repairing, augmenting and/or replacing tissues and organs.