DERIVES DE 2,3-DIHYDROIMIDAZO [1,2-C] QUINAZOLINE A SUBSTITUTION SULFONE UTILISES POUR TRAITER DES TROUBLES HYPERPROLIFERANTS ET DES MALADIES ASSOCIEES A L'ANGIOGENESE
SCOTT, WILLIAM,WOOD, JILL,JOHNSON, JEFFREY,REDMAN, ANIKO,BULLION, ANN-MARIE,GUERNON, LEATTE,HENTEMANN, MARTIN F.
申请号:
CA2713388
公开号:
CA2713388C
申请日:
2009.01.13
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
This invention relates to novel sulfone 2I3-dihydroimidazo[1 12-c]quinazolinecompounds, pharmaceuticalcompositions containing such compounds and the use of those compounds orcompositions for phosphotidylinositol-3-kinase (P13K)in-hibition and treating diseases associated with phosphotidylinositol-3-kinase (P13K) activity, in particular treatinghyper-proliferative and/or angiogenesis mediated disorders, as a sole agent orin combination with other active ingredients.