Sulfone substituted 2,3-dihydroimidazo [1,2-C] quinazoline derivatives useful for treating hyper-proliferative disorders and diseases with angiogenesis
Ann-Marie Bullion;Leatte Guernon;William Scott;Aniko Redman;Jill Wood;Jeffrey Johnson;Martin F. Hentemann
发明人:
Martin F. Hentemann,William Scott,Jill Wood,Jeffrey Johnson,Aniko Redman,Ann-Marie Bullion,Leatte Guernon
申请号：
US12812911
公开号：
US08859572B2
申请日:
2009.01.13
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This invention relates to novel sulfone 2I3-dihydroimidazo[1 l2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis mediated disorders, as a sole agent or in combination with other active ingredients.
