PROBLEM TO BE SOLVED: To provide a method for producing a dry delivery system comprising xerogel or a film which can deliver stable or unstable active substances to a topical part or can release the same in advantageous release dynamics.SOLUTION: The method for producing a dry delivery system for a medical supply and/or a cosmetic includes: a step (i) of preparing a liquid in which at least one active ingredient is dissolved or dispersed a step (ii) of sterilizing the liquid a step (iii) of preparing the dry carrier of a xerogel or a film and sterilizing the same a step (iv) of applying the fine droplets of the liquid to the surface region of at least one of the dry carrier of the xerogel or film obtained in the step (iii) and a step (v) of repeating the step (iv) at least one time or directly transferring to the following step (vi) and repeating the steps (i) to (v) at least one time using a liquid including another active ingredient or directly transferring to the following step (vii) and vacuum-drying or freeze-drying the system obtained in the above step.COPYRIGHT: (C)2012,JPO&INPIT【課題】安定若しくは不安定な活性物質の局所への送達若しくは有利な放出動態で放出することができるキセロゲル又はフィルムを含む乾燥送達系の製造方法の提供。【解決手段】(i)少なくとも1つの活性成分を溶解又は分散した液体を調製する工程;(ii)該液体を滅菌する工程;(iii)キセロゲル又はフィルムの乾燥担体を調製し、そして滅菌する工程;(iv)前記記載の液体の微液滴を、工程(iii)で得られたキセロゲル又はフィルムの乾燥担体の少なくとも1つの表面領域に塗布する工程;(v)工程(iv)を少なくとも1回繰り返す工程、又は直接次の工程(vi)にうつり;および(vi)別の活性成分を含む液体を用いて工程(i)~(v)を少なくとも1回繰り返す工程、又は直接次の工程(vii)にうつり;(vii)上記工程で得られた系を真空乾燥又は凍結乾燥する工程を含む医療品用及び/又は化粧品用の送達系を製造する方法。【選択図】図1
