The present application relates to novel substituted 4-aryl-1,4-dihydro-1,6-naphthyridine-3-carboxamides, a process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovaseular disorders.本案有關新穎之經取代4-芳基-1,4-二氫-1,6-啶-3-甲醯胺、其製備方法、其用於治療及/或預防疾病之用途及其用以製造供治療及/或預防尤其是心血管病症的疾病使用之藥劑的用途。