The present application relates to novel trifluoromethyl-substituted fused pyrimidines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.本發明係關於新穎經三氟甲基取代之稠合嘧啶,關於其製備方法,關於其等單獨或合併以治療及/或預防疾病的用途,且關於其等於製備用來治療及/或預防疾病,特別為治療及/或預防心血管病症之醫藥品的用途。