The invention pertains to a device for resonance intracellular transport wherein said device can be connected to two electrodes, wherein a first of said electrodes is configured to contain an active principle to be administered by an intracellular route, the device comprising a wave generator configured to generate a driving signal to be sent to said electrodes, wherein said driving signal comprises a plurality of packets grouped in trains of packets and in groups of trains, wherein each packet consists of a unidirectional signal resulting from the combination of a modulating signal and a carrier signal, wherein each train of packets consists of a series of packets, wherein each group of trains comprises a series of trains of packets, and said wave generator is configured to reverse the polarity of said trains of packets, characterised in that the device is configured to generate a driving signal having a first depth frequency of the carrier signal correlated to the depth of an organ or of a tissue to be treated and at least a second depth frequency correlated to the thickness of the said organ or tissue, and to generate resonance frequencies expressed by the repetition frequency of the packets, by the repetition frequency of the trains of packets and by the repetition frequency of the groups of trains.L'invention concerne un dispositif de transport intracellulaire en résonance, ledit dispositif pouvant être connecté à deux électrodes, une première desdites électrodes étant configurée pour contenir un principe actif à administrer par voie intracellulaire, le dispositif comprenant un générateur d'ondes configuré pour générer un signal d'entraînement à envoyer auxdites électrodes, ledit signal d'entraînement comprenant une pluralité de paquets groupés en trains de paquets et en groupes de trains, chaque paquet étant constitué d'un signal unidirectionnel résultant de la combinaison d'un signal de modulation et d'un signal de porteuse, chaque train de paquets étant cons
