There is provided a drug dispenser device comprising a housing； extending from the housing, an outlet for insertion into a body cavity of a patient； provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet； connecting to the drug discharge device, a container collar； connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion； provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction； linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction； and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome.
