BIOMARKERS FOR ADIPOSE TISSUE ACTIVITY
- 专利权人:
- 发明人:
- PFUETZNER ANDREAS
- 申请号：
- IN3184/KOLNP/2011
- 公开号：
- IN2011KN03184A
- 申请日:
- 2011.07.27
- 申请国别(地区):
- IN
- 年份:
- 2012
- 代理人:
- 摘要：
The invention provides compositions and methods for determining a subjects adipose tissue activity. In one embodiment, the composition comprises a solid support comprising probes for measuring a biomarker panel comprising, for example, adiponectin, resistin, PAI-1, optionally leptin and optionally visfatin. The simultaneous use of multiple biomarkers with independent classification power will increase the performance of the biomarker panel in identifying adipose tissue activity, which is associated with various disease states including chronic or systemic inflammation, atherosclerosis and other cardiovascular risks and complications. The invention also provides methods of treating a subject and determining the efficacy of a therapy through assaying the various biomarkers of a biomarker panel disclosed herein.
[WO2010076655A1]
- 来源网站：
- 中国工程科技知识中心
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