< Topic >The effective chronic blockade characteristic lung diseased remedy medicine is offered.SolutionsGeneral system:[In formula, as for A the low-grade alkylene basis, as for R as for connection between 3 rank and 4 ranks of shikuroarukiru and the karubosuchiriru framework single connection or double bond is shown]So the karubosuchiriru derivative or that salt, and designates purobukoru as the active ingredient the chronic blockade characteristic lung diseased remedy medicine which are shown.< Selective figure >It is not【課題】効果的な慢性閉塞性肺疾患治療剤を提供する。【解決手段】一般式:[式中、Aは低級アルキレン基、Rはシクロアルキル基、カルボスチリル骨格の3位と4位間の結合は一重結合又は二重結合を示す]で示されるカルボスチリル誘導体またはその塩、及びプロブコールを有効成分とする慢性閉塞性肺疾患治療剤。【選択図】なし
