A system and method for determining the position of objects in a radiation room for radiation therapy comprises several room lasers arranged in the radiation room, each of which is designed for patient positioning to project at least one laser line onto the surface of a patient located on a patient table in the radiation room. At least one camera detects at least one laser line projected onto the surface of the patient by at least one of the room lasers, and an evaluation and control apparatus determines the coordinate points along the laser line projected onto the surface of patient during a radiation procedure based on measurement values detected by the camera through a real-time triangulation process and compares them with target coordinate points. The coordinate points determined during the radiation procedure may be saved for documentation of the radiation procedure.