PROBLEM TO BE SOLVED: To provide a disease onset risk change early stage warning system capable of accurately measuring a head blood pressure when acquiring living body information and predicting a disease onset risk change.SOLUTION: The invention detects a mastication behavior in addition to observation of a pulse wave in a non-invasion state, and predicts blood pressure elevation with consideration of the mastication behavior.SELECTED DRAWING: Figure 1【課題】生体情報を取得して疾病発症危険度変化を予測する際に、頭部血圧を精度よく測定することのできる疾病発症危険度変化早期警報システムを提供する。【解決手段】非侵襲で脈波を観測する以外に咀嚼行動を検出し、これを加味して血圧上昇予測をする。【選択図】図1