PROBLEM TO BE SOLVED: To provide a method for: (i) reducing the number of cancer cells of cancer that consists of breast cancer, lung cancer, ovarian cancer, endometrial cancer, stomach cancer, rectal cancer, head and neck cancer, and pancreatic cancer (ii) reducing a tumor volume (iii) increasing a tumor reduction rate (iv) reducing or delaying cancer cell infiltration to peripheral organs (v) reducing or delaying tumor metastasis (vi) reducing or preventing tumor proliferation (vii) preventing or delaying occurrence of cancer and/or recurrence of cancer, and/or extending a disease-free survival time or a tumor-free survival period (viii) increasing an overall survival period (ix) reducing frequency of treatment and/or (x) alleviating one or more symptom related to cancer.SOLUTION: Eribulin (e.g., eribulin mesylate) is administrated in combination with S-1 or 5-FU.COPYRIGHT: (C)2016,JPO&INPIT【課題】乳がん、肺がん、卵巣がん、子宮内膜がん、胃がん、直腸がん、頭頸部がん、及び膵がんからなるがんの、(i)がん細胞の数を減らし、(ii)腫瘍体積を減らし、(iii)腫瘍縮小率を増加させ、(iv)末梢器官へのがん細胞浸潤を減らすか若しくは遅らせ、(v)腫瘍転移を減らすか若しくは遅らせ、(vi)腫瘍増殖を減らすか若しくは妨げ、(vii)がんの発生及び/若しくはがんの再発を妨げるか若しくは遅らせ、並びに/又は無病生存時間若しくは腫瘍のない生存期間を延長させ、(viii)全体の生存期間を増加させ、(ix)治療の頻度を減らし、並びに/又は(x)がんに関連した一つもしくはそれ以上の病状を緩和する方法の提供。【解決手段】エリブリン(例えばエリブリンメシラート)をS-1もしくは5-FUと併用して投与する。【選択図】なし
