TAO, Zhi-Fu,DOHERTY, George,WANG, Xilu,SULLIVAN, Gerard M.,SONG, Xiaohong,KUNZER, Aaron R.,WENDT, Michael D.,FREY, Robin R.,CULLEN, Steve C.,WELCH, Dennie S.,SHEN, Xiaoqiang,BENNETT, Nathan B.,HAIGHT,
申请号：
AU2020210220
公开号：
AU2020210220A1
申请日:
2020.07.29
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020210220A120200820.pdf#####ABSTRACT Small molecule Bcl-xL inhibitorsand Antibody Drug Conjugates (ADCs) comprising small molecule Bcl-xL inhibitors are disclosed herein. The Bcl-xL inhibitors and ADCs of the disclosure are useful for, among other things, inhibiting anti-apoptotic Bcl-xL proteins as a therapeutic approach towards the treatment of diseases that involve a dysregulated apoptosis pathway.
