Scars, stretch marks, keloids, keratosis, and other skin lesions can be ameliorated through topical application of a composition containing a fortified botanical complex inhibiting tryptase and chymase. A flavonoid with antioxidant properties valuable in inflammatory stress blocking the release of histamine, inhibiting leukocytic elastase and strengthening the protective properties surrounding the extracellular matrix. Primary wound healing occurs through the release of platelet derived growth factors stimulating the production of procollagen and increasing the density of water holding skin matrix cells which provide unencumbered moisture to the skin. The formula peptides are matrikines They act in synergy to restore and maintain the skins appearance by activating the neosynthesis of extracellular matrix molecules. As messenger molecules the matrikines are capable of regulating cell activities: they interact with specific receptors to activate certain genes involved in extracellular matrix renewal and cell proliferation. Peptides also provide a major role in restructuring and restoring collagen.
