KRASUTSKY, ALEXEI PAVLOVYCH,SNYDER, NANCY JUNE,WALLACE, OWEN BRENDAN,XU, YANPING,YORK, JEREMY SCHULENBURG
申请号:
PL07761153
公开号:
PL2049475T3
申请日:
2007.04.24
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The present invention discloses novel compounds of Formula I: having 11&bgr;-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11&bgr;-HSD type 1 activity.