Su Jeong KIM,Sang Eun NOH,Jun Ho LEE,Hyeon Youl LEE,Kyoung Baek CHOI,Heon Sik CHOI
申请号:
US16627541
公开号:
US20200124590A1
申请日:
2018.06.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a method for evaluating effectiveness of a cell therapeutic agent. When using TGF-β and/or TSP-1 expression level(s) in: (a) a first population of transformed mammalian cells with TGF-β; and (b) a second population of untransformed mammalian cells with the same gene, respectively, as a criterion for determining effectiveness of a cell therapeutic agent, and whether or not expression thereof, it is possible to definitely determine the therapeutic efficacy of each cell therapeutic agent prior to initiation of the treatment. In addition, since use of a cell therapeutic agent without therapeutic effects is avoided, undesired procedures and side effects may not be entailed.