BINDER, Joseph John,CHO, Helen Kim,DERMYER, Michael Robert,JOOSS, Karin Ute,PIERCE, Brian Gregory,TAN, Joyce Tsi,TSAI, Van To
申请号:
AU2016202651
公开号:
AU2016202651A1
申请日:
2016.04.27
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016202651A120160519.pdf#####H: ft interwoven NRPortbl DCC FMT l0026890_ .docx-21/04/2016 ABSTRACT The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c) vaccine compositions comprising an immunogenic PAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic PAA polypeptide; (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions; and (e) vaccine-based immunotherapy regimens which involve co-administration of a vaccine in combination with an immune-suppressive-cell inhibitor and an immune-effector-cell enhancer.