Provide a kind of device, it includes the main structure with one or more surfaces, wherein at least one surface includes pH sensitive layer, the pH sensitive layer Bao Han Line type polymer, wherein the water solubility in pH trigger value when Suo Shu Line type polymer increases to the second water solubility from the first water solubility. Also illustrate the method to form device, and prevention or the method for mitigating infection.提供了一種裝置,其包括具有一個或多個表面的主體結構,其中至少一個表面包含pH敏感層,該pH敏感層包含綫型聚合物,其中在pH觸發值時所述綫型聚合物的水溶解度從第一水溶解度增加到第二水溶解度。也描述了形成裝置的方法,以及預防或减輕感染的方法。