THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)
发明人:
NA, MIN KYUNKR,나민균,BAE, JONG SUPKR,배종섭
申请号:
KR1020150078819
公开号:
KR1020160142723A
申请日:
2015.06.03
申请国别(地区):
KR
年份:
2016
代理人:
摘要:
The present invention relates to a composition comprising quinic acid derivatives for preventing or treating sepsis. The composition inhibits expression of high mobility group box 1 (HMGB1), and inhibits a death rate according to cecal ligation and puncture (CLP) operation, thereby being used as a composition for preventing or treating sepsis or a health functional food for preventing or alleviating sepsis.COPYRIGHT KIPO 2016본 발명은 퀴닉산 유도체(Quinic acid derivatives)를 함유하는 패혈증의 예방 또는 치료용 조성물에 관한 것으로서, 상기 조성물은 HMGB1(high mobility group box 1)의 발현을 억제하고, CLP 수술법(cecal ligation and puncture operation)에 따른 사망률을 억제하는 효과가 우수하여, 패혈증의 예방 또는 치료용 조성물이나 패혈증의 예방 또는 개선용 건강기능식품으로 용이하게 이용가능하다.