Anti-cancer tocotrienol analogues and associated methods

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专利权人:

Paul W. Sylvester

发明人:

Paul W. Sylvester,Khalid A. El Sayed

申请号：

US12766047

公开号：

US08268786B2

申请日:

2010.04.23

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Compounds are disclosed relating to the treatment of cancer that include tocotrienols and derivatives of tocotrienols including 2,5,7,8-tetramethyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-ylphenylsulfonylcarbamate (R)-2,8-dimethyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-yl tosylcarbamate and (R)-2,5,7,8-tetramethyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-yl benzylcarbamate. Therapeutic uses of these types of compounds are also taught.

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