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COMPOSE IMIDAZOPYRIDINE
专利权人:
ASTELLAS PHARMA INC.
发明人:
KOGA, YUJI,MAENO, KYOICHI,SATO, IPPEI,IMAMURA, YOSHIMASA,HANAZAWA, TAKESHI,IIDA, MAIKO,OHNE, KAZUHIKO,IMAMURA, KENICHIRO,WATANABE, TSUBASA,NOZAWA, EISUKE,SHIBATA, HIROSHI
申请号:
CA2836202
公开号:
CA2836202A1
申请日:
2012.05.29
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
[Problem] To provide an excellent therapeutic or prophylactic agent for cardiovascular diseases on the basis of cGMP production-increasing activity attributed to soluble guanylate cyclase-activating activity. [Solution] It was discovered that an imidazopyridine compound having a carbamoyl group at the 3-position of an imidazo[1,2-a]pyridine skeleton and having a substituent attached to the 8-position of the skeleton through an oxygen atom exhibits cGMP production-increasing activity attributed to potent soluble guanylate cyclase-activating activity and can be used in an excellent therapeutic or prophylactic agent for various cardiovascular diseases associated with soluble guanylate cyclase, and the invention was completed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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