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COMPOSÉS IMIDAZOPYRIDINE
专利权人:
Astellas Pharma Inc.
发明人:
申请号:
EP13858992.4
公开号:
EP2927231A1
申请日:
2013.11.28
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
[Problem]A pharmaceutical composition for treating or preventing various cardiovascular diseases, which have sGC activities based on improvement of cGMP signals, is provided.[Means for Solution]It was found that imidazo[1,2-a]pyridine compounds having a carbamoyl group at the 3-position and a particular cyclic group at the 8-position via a methyleneoxy group, or a salt thereof have sGC activation, and are useful as active ingredients of pharmaceutical compositions for treating or preventing various sGC-related cardiovascular diseases, in particular, peripheral arterial diseases, intermittent claudication, critical limb ischemia, hypertension, and pulmonary hypertension, thereby completing the present invention.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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