Disclosed in certain embodiments is a solid oral dosage form comprising a plurality of particles, each particle comprising (i) a core comprising an active agent susceptible to abuse and an internal adhesion promoter, wherein the cores are (i) dispersed in a matrix comprising a controlled release material or (ii) coated with a controlled release material. The dosage form can also include an alcohol resistant material.本發明在某些實施例中揭示一種包含複數個粒子之固體口服劑型，各粒子包含(i)包含容易濫用之活性劑及內部增黏劑之核心，其中該等核心(i)分散於包含控制釋放材料之基質中或(ii)包覆控制釋放材料。該劑型亦可包括抗酒精材料。
