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Tamper resistant immediate release formulations
专利权人:
Purdue Pharma L.P.
发明人:
Reilly, Kevin
申请号:
AU2012310251
公开号:
AU2012310251A1
申请日:
2012.09.14
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Disclosed in certain embodiments is an oral dosage form comprising a plurality of particles, each particle comprising (i) a core comprising a gelling agent (ii) an optional barrier layer encompassing the core (iii) an active layer comprising a drug susceptible to abuse encompassing the core or barrier layer and (iv) an optional controlled release excipient wherein the dosage form provides an immediate or controlled release and wherein the viscosity of the dosage form mixed with from about 0.5 to about 10 ml of an aqueous liquid is unsuitable for parenteral or nasal administration.
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