Chu-Biao Xue,Genfeng Cao,Taisheng Huang,Lihua Chen,Ke Zhang,Anlai Wang,David J. Meloni,Rajan Anand,Joseph Glenn,Brian W. Metcalf
申请号：
US13564434
公开号：
US08680104B2
申请日:
2012.08.01
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to compounds of Formula I:wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR5. The compounds can be used, for example, to treat diseases associated with chemokine receptor expression or activity such as inflammatory diseases, immune diseases and viral infections.
