Methods for the prevention, treatment or management of sexual dysfunction, such as premature ejaculation, by administering to a patient in need of therapy a therapeutically effective amount of a rapid-onset selective serotonin reuptake inhibitor on an as-needed basis shortly before sexual activity.本發明提供一種用於預防、治療或處理性官能障礙(如:提早射精)之以需要為基礎之醫藥組合物,其包括醫療有效量之快速開始選擇血清素再攝入抑制劑。