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thienopyrimidines
- 专利权人:
- Bayer Pharma Aktiengesellschaft
- 发明人:
- KETTSCHAU, Georg,PÜHLER, Florian,EIS, Knut,KLAR, Ulrich,KOSEMUND, Dirk,SÜLZLE, Detlev,LIENAU, Philip,HÄGEBARTH, Andrea,BÖMER, Ulf,WORTMANN, Lars,GRAHAM, Keith,WENGNER, Antje Margret
- 申请号：
- ES13725935
- 公开号：
- ES2591129T3
- 申请日:
- 2013.05.17
- 申请国别(地区):
- ES
- 年份:
- 2016
- 代理人:
- 摘要：
- A compound of general formula (I): ** Formula ** in which: R1 represents a group selected from: -C (>； = O) O-R3, -C (>； = O) N (H) R3, - C (>； = O) NR3R4； R2a, R2b, R2c, R2d independently represent each other, a hydrogen atom or a group selected from: C1-C3- alkyl, C1-C3 alkoxy-, halo-, hydroxy-, C1-C3 haloalkyl-, C1- haloalkoxy C3-, cyano-, -N (H) R5, -NR5R4； R3 represents a hydrogen atom or a group selected from: C1-C6- alkyl, C2-C6 alkenyl, C2-C6- alkynyl, - (CH2) q- (C3-C7 cycloalkyl), - (CH2) qO- ( C3-C7 cycloalkyl), - (CH2) q- (C4-C7 cycloalkenyl), - (CH2) qO- (C4-C7 cycloalkenyl), - (CH2) q- (3 to 10-membered heterocycloalkyl), - (CH2 ) qO- (3 to 10-membered heterocycloalkyl), - (CH2) q- (4 to 10-membered heterocycloalkenyl), - (CH2) qO- (4 to 10-membered heterocycloalkenyl), - (CH2) q-aryl, - (CH2) qO-aryl, - (CH2) q-heteroaryl, - (CH2) qO-heteroaryl； said group being optionally substituted, one or more times, identically or differently, with a substituent selected from: halo-, hydroxy-, oxo- (O>； =), cyano-, nitro-, C1-C6 alkyl-, alkenyl C2-C6-, C2-C6- alkynyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C6 hydroxyalkyl, C1-C6 alkoxy-C1-C6 alkyl-, - (CH2) q-aryl, - (CH2) q-heteroaryl, - (CH2) q- (C3-C7 cycloalkyl), - (CH2) q- (3-10 membered heterocycloalkyl), C1-C6 haloalkoxy-C1-C6 alkyl- , R5-O-, -C (>； = O) R5, -C (>； = O) O-R5, -OC (>； = O) R5, -N (H) C (>； = O) R5, -N (R4) C (>； = O) R5, -N (H) C (>； = O) NR5R4, -N (R4) C (>； = O) NR5R4, -N (H) R5, -NR5R4, -C ( >； = O) N (H) R5, -C (>； = O) NR5R4, R4-S-, R4-S (>； = O), R4-S (>； = O) 2, -N (H) S ( >； = O) R4, -N (R4) S (>； = O) R4, -S (>； = O) N (H) R5, -S (>； = O) NR5R4, -N (H) S (>； = O) 2R4, -N (R4) S (>； = O) 2R4, -S (>； = O) 2N (H) R5, -S (>； = O) 2NR5R4, -S (>； = O) (>； = NR5 ) R4, S (>； = O) (>； = NR4) R5, -N>； = S (>； = O) (R5) R4； or when two substituents are present in ortho position with one another in an aryl or heteroaryl rin
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
