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INDAZOLE AND PYRAZOLOPYRIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
COOK BRIAN NICHOLAS,KUZMICH DANIEL,MAO CAN,RAZAVI HOSSEIN
申请号:
TN2012000180
公开号:
TN2012000180A1
申请日:
2012.04.19
申请国别(地区):
TN
年份:
2013
代理人:
摘要:
Diclosed are CCRl receptor antagonists of the formula (I), wherein X is nitrogen or, C-R2; Ar1 is carbocycle, heteroaryl or heterocyclyl each optionally substituted by one to three Ra; Ar2 is carbocycle, heteroaryl or heterocyclyl, each optionally substituted by one to three Rb; Cyclic G is carbocycle, or heterocyclyl each optionally substituted by one to two R8; R1 is hydrogen, C1-6 alkyl or C 1-6 alkoxyC1-6 alkyl. Also disclosed are compositions, methods of making and using compounds of the formula (I).
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