BERNICK, BRIAN A.,AMADIO, JULIA M.,PERSICANER, PETER H.R.,CACACE, JANICE LOUISE,IRANI, NEDA
申请号：
EP13807463
公开号：
EP2861233A4
申请日:
2013.06.18
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Pharmaceutical formulations for oral use in hormone replacement therapy comprising ultra-micronized progesterone are disclosed, wherein the ultra-micronized progesterone is combined with a suitable excipient. The preferred excipients comprise medium chain fatty acid-glycol esters and a nonionic surfactant comprising a polyethylene glycol fatty acid ester. In some embodiments C8 to C18 fatty acid esters of glycerol and polyethylene glycol are the preferred nonionic surfactants.
