Progesterone Formulations

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专利权人:

Inc.;TherapeuticsMD

发明人:

CACACE, Janice Louise,PERSICANER, Peter H. R.

申请号：

AU2018222947

公开号：

AU2018222947A1

申请日:

2018.08.29

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2018222947A120180920.pdf#####ABSTRACT 120 10 --- Formvvoo 402 -. - Existn PrcdudA1 0 10 20 30 40 50 60 70 Time (Mi W&tes) PG. 4 Pharmaceutical formulations for oral use in hormone replacement therapy comprising ultra-micronized progesterone are disclosed, wherein the ultra-micronized progesterone is combined with a suitable excipient. The preferred excipients comprise medium chain fatty acid-glycol esters and a nonionic surfactant comprising a polyethylene glycol fatty acid ester. In some embodiments C8 to C18 fatty acid esters of glycerol and polyethylene glycol are the preferred nonionic surfactants.

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