METHODS AND COMPOSITIONS FOR MODIFYING MACROPHAGE POLARIZATION INTO PRO-INFLAMMATORY CELLS TO TREAT CANCER

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专利权人:

发明人:

Nicolas Poirier,Bernard Vanhove,Vanessa Gauttier

申请号：

US15769689

公开号：

US20180312600A1

申请日:

2016.10.21

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present disclosure concerns the use of an anti-SIRPa compound able to inhibit the polarization of anti-inflammatory M2-type macrophages and/or favors pro-inflammatory M1-type macrophages. In a preferred embodiment, such compound is used to treat cancer. Interestingly, this disclosure allows to treat cancer through an indirect pathway involving the immune system.

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http://www.ckcest.cn/home/