METHODS AND COMPOSITIONS FOR MODIFYING MACROPHAGE POLARIZATION INTO PRO-INFLAMMATORY CELLS TO TREAT CANCER

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专利权人:

オーエスイー イムノセラピューティクス

发明人:

ポワリエ,ニコラ,ヴァンノーヴ,ベルナール,ゴティエ,ヴァネッサ

申请号：

JP2018521040

公开号：

JP2018531274A6

申请日:

2016.10.21

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The present disclosure concerns the use of an anti-SIRPa compound able to inhibit the polarization of anti-inflammatory M2-type macrophages and/or favors pro-inflammatory M1-type macrophages. In a preferred embodiment, such compound is used to treat cancer. Interestingly, this disclosure allows to treat cancer through an indirect pathway involving the immune system.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/