WU, MING JUNG,吴明忠,吳明忠,LO, YU HSIANG,罗宇翔,羅宇翔,LU, PEI JUNG,吕佩融,呂佩融,HONG, YI REN,洪义人,洪義人
申请号:
TW098139712
公开号:
TWI398245B
申请日:
2009.11.23
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
Disclosed herein are novel 5-[6-aryl-3(Z)-hexen-1,5-diynyl]-1,2,3-trimethoxybenzene compounds of formula (I):or a pharmaceutically acceptable salt thereof, wherein each of the substituents is given the definition as set forth in the Specification and Claims.Also disclosed are the uses of these compounds in the manufacture of pharmaceutical compositions for use in the treatment of cancers.本發明揭示具有下列化學式(I)之新穎的5-[6-芳基-3(Z)-己烯-1,5-二炔基]-1,2,3-三甲氧基苯化合物:或者它們的一藥學上可接受的鹽類,其中各個取代基的定義是如說明書與申請專利範圍中所界定者。本發明亦揭示此等化合物在製備供用於治療癌症的藥學組成物上的用途。