Disclosed are a device, a method, and a system for for obtaining more than one biological fluid component using a back-flushable filter device, and reducing the red blood cell contamination. The device includes: a housing which comprises an inflow port and an outflow port, and limits a fluid path in between the inflow port and the outflow port and a porous fibrous leukocyte removal filter with an upstream surface and a downstream surface, located on the housing after passing through the fluid path.COPYRIGHT KIPO 2014역류형(back-flushable) 필터 장치를 사용하여, 하나 이상의 생물학적 유체 성분을 수득하고, 적혈구 세포 오염을 감소시키기 위한 장치, 방법 및 시스템이 개시된다.