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METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENTS
专利权人:
ВЭРИЭЙШН БИОТЕКНОЛОДЖИЗ; ИНК. (CA)
发明人:
КИРХМАЙЕР Марк Джей (US),АНДЕРСОН Дэвид И. (US)
申请号:
RU2014133089
公开号:
RU2014133089A
申请日:
2013.01.25
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. Thermostable lyophilized composition containing: a drug or lipid component, consisting of one or more nonionic surfactants (surfactant) .2. The composition of claim 1, wherein the lipid component consists of 1-monopalmitoylglycerol (MPG). A thermostable lyophilized composition comprising: a drug or lipid component, consisting of one or more nonionic surfactants and one or more steroids. 4. The composition of claim 3, wherein the lipid component consists of 1-monopalmitoylglycerol (MPG) and cholesterol (CHO). Thermostable lyophilized composition containing: a drug and preformed vesicles that contain a nonionic surfactant, a steroid and an ionic amphiphilic substance. 6. The composition of claim 5, wherein the ionic amphiphilic substance is dicetyl phosphate (DCP). The composition of claim 5, wherein the ionic amphiphilic substance is diphosphatidylglycerol (DPPG). The composition of claim 6, wherein the nonionic surfactant is 1-monopalmitoylglycerol (MPG) and the steroid is cholesterol (CHO). The composition of claim 7, wherein the nonionic surfactant is 1-monopalmitoylglycerol (MPG) and the steroid is cholesterol (CHO). Thermostable lyophilized composition containing: a medicinal product and vesicles that contain a nonionic surfactant, steroid and phosphoglyceride. 11. The composition of claim 10, wherein the phosphoglyceride is diphosphatidylglycerol (DPPG). The composition of claim 11, wherein the nonionic surfactant is 1-monopalmitoylglycerol (MPG) and the steroid is cholesterol (CHO). Composition according to any one of paragraphs. 1-12, where the drug contains a weakened virus1. Термостабильная лиофилизованная композиция, содержащая:лекарственное средство илипидный компонент, состоящий из одного или более неионогенных ПАВ (поверхностно-активное вещество).2. Композиция по п. 1, где липидный компонент состоит из 1-монопальмитоилглицерина (MPG).3. Термостабильная лиофилизованная композиция, содержащая:лекарственное средство илипидный компонент, состоящий из одн
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