Victoria M. Richon;Roy M. Pollock;Scott R. Daigle;Edward J. Olhava;Kevin W. Kuntz;Richard Chesworth
发明人:
Edward J. Olhava,Richard Chesworth,Kevin W. Kuntz,Victoria M. Richon,Roy M. Pollock,Scott R. Daigle
申请号:
US13310157
公开号:
US20120142625A1
申请日:
2011.12.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to substituted purine and 7-deazapurine compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders, by administering these compounds and pharmaceutical compositions to subjects in need thereof.