Edward J. OLHAVA,Richard CHESWORTH,Kevin Wayne KUNTZ,Victoria M. RICHON,Roy M. POLLOCK,Scott R. DAIGLE
申请号:
US15802979
公开号:
US20180280422A1
申请日:
2017.11.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to substituted purine and 7-deazapurine compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders, by administering these compounds and pharmaceutical compositions to subjects in need thereof.