Pochodne triazoliloimidazopirydyny i triazolilopuryny, zawierająca je kompozycja farmaceutyczna, ich zastosowanie, sposób ich otrzymywania oraz związki pośrednie wykorzystywane w tym sposobie

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专利权人:

SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.

发明人:

TARZIA GIORGIO,GIORGIO TARZIA,PIERSANTI GIOVANNI,GIOVANNI PIERSANTI,MINETTI PATRIZIA,PATRIZIA MINETTI,DI CESARE MARIA ASSUNTA,MARIA ASSUNTA DI CESARE,GALLO GRAZIA,GRAZIA GALLO,GIORGI FABRIZIO,FABRIZIO,FABRIZIO GIORGI,GIORGI F

申请号：

PL368409

公开号：

PL217269B1

申请日:

2002.07.25

申请国别(地区):

PL

年份:

2014

代理人:

摘要：

Compounds of formula (I) wherein: X is N； R<；SUB>；1 <；/SUB>；is C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；linear or branched alkyl or C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；linear or branched alkenyl； R<；SUB>；2 <；/SUB>；is hydrogen, C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；linear or branched alkyl or C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；linear or branched alkenyl, C<；SUB>；6<；/SUB>；-C<；SUB>；14 <；/SUB>；aryl or C<；SUB>；6<；/SUB>；-C<；SUB>；14 <；/SUB>；aryl(C<；SUB>；1<；/SUB>；-C<；SUB>；6<；/SUB>；) linear or branched alkyl or C<；SUB>；6<；/SUB>；-C<；SUB>；14 <；/SUB>；aryl(C<；SUB>；1<；/SUB>；-C<；SUB>；6<；/SUB>；) linear or branched alkenyl, with the aryl group optionally substituted by one or more substituents, either the same or different, selected from the group consisting of halogen, hydroxy, C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；alkoxy linear or branched or C<；SUB>；1<；/SUB>；14 C<；SUB>；6 <；/SUB>；alkenyloxy linear or branched, amino, optionally mono- or disubstituted with C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；linear or branched alkyl； R<；SUB>；3 <；/SUB>；is NH<；SUB>；2<；/SUB>；, NHR<；SUB>；4<；/SUB>；； R<；SUB>；4 <；/SUB>；is C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；alkyl or C<；SUB>；1<；/SUB>；-C<；SUB>；6 <；/SUB>；hydroxyalkyl, C<；SUB>；1<；/SUB>；-C<；SUB>；3 <；/SUB>；alkoxyalkyl, amino(C<；SUB>；1<；/SUB>；-C<；SUB>；6<；/SUB>；)alkyl, where the amino group is optionally substituted with one or two C<；SUB>；1<；/SUB>；-C<；SUB>；3 <；/SUB>；linear or branched alkyl groups, or with one or two C<；SUB>；2<；/SUB>；-C<；SUB>；3 <；/SUB>；alkenyl groups C<；SUB>；6<；/SUB>；-C<；SUB>；14 <；/SUB>；aryl or C<；SUB>；6<；/SUB>；-C<；SUB>；14 <；/SUB>；aryl(C<；SUB>；1<；/SUB>；-C<；SUB>；6<；/SUB>；)alkyl

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