NIP THIAZOLE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1

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专利权人:

MERCK PATENT GMBH

发明人:

LERICHE CAROLINE,CARNIATO DENIS,ROCHE DIDIER,CHARON CHRISTINE,DOARE LILIANE

申请号：

ZA201008723

公开号：

ZA201008723B

申请日:

2010.12.03

申请国别(地区):

ZA

年份:

2012

代理人:

摘要：

The present invention relates to NIP thiazole derivatives of formula (I) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/