ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI;STICHTING KATHOLIEKE UNIVERSITEIT
发明人:
WILLEM MULDER,JORDI OCHANDO,ZAHI FAYAD,MIHAI NETEA,LEO JOOSTEN
申请号：
US16862564
公开号：
US20200253884A1
申请日:
2020.04.30
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to therapeutic nanobiologic compositions and methods of treating patients who have cancer, by promoting trained immunity, which is the long-term increased responsiveness, the result of metabolic and epigenetic re-wiring of myeloid cells and their stem cells and progenitors in the bone marrow and spleen and blood induced by a primary insult, and characterized by increased cytokine excretion after re-stimulation with one or multiple secondary stimuli.
