ADAM12 Inhibitors and Their Use Against Inflammation-Induced Fibrosis

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专利权人:

Institut Pasteur

发明人:

Lucie Peduto,Gerard Eberl

申请号：

US15690076

公开号：

US20170369888A1

申请日:

2017.08.29

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to the field of fibrosis and inflammation and more particularly to the use of ADAM12 (A Disintegrin and Metalloproteinase 12) inhibitors to prevent or treat inflammation-induced fibrosis. The present invention also relates to the use of ADAM12 as a marker for inflammation-induced fibrosis and to the ablation of ADAM12 expressing cells as therapeutic approach to interfere with the development of pro-fibrotic cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/